For detailed information on NVIDIA GPU support, refer to the CN5000 Fabric Installation Guide, NVIDIA GPU Requirements.

For GPUDirect to function properly, NVIDIA recommends disabling PCIe Access Control Services (ACS), also known as IO virtualization or IOMMU. If left enabled, unpredictable behavior such as application failures may be experienced. Refer to the NVIDIA documentation, PCI Access Control Services, for more information regarding this setting. Additionally, on AMD CPU platforms, you must set iommu=pt as a kernel boot parameter.